Pathophysiology of Cerebral Ischemia: Role of Oxidative/Nitrosative Stress
نویسندگان
چکیده
منابع مشابه
Pathophysiology of cerebral ischemia.
The purpose of this manuscript is to briefly review the pathophysiology of cerebral ischemia. Ischemic thresholds are well-defined in lower animals. The concept of the ischemic penumbra may include regions of brain around deeper regions of ischemia but has also been defined in terms of brain salvageable by reperfusion or by pharmacological therapies. The principal pathophysiological processes i...
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Evidences obtained from the past two decades showed that there is an involvement of reactive oxygen species in cerebral ischemia (Christophe and Nicolas 2006). Thrombolytic reperfusion or reoxygenation during spontaneous perfusion provides oxygen as a substrate for various enzymatic reactions in the subcellular organelles or cytosolic compartments and mitochondria that will further increase oxi...
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A small percentage of patients who suffer a global cerebral hypoxic/ischemic event develop reversal of the normal density relationships of gray and white matter on CT. CT and pathologic findings in the three cases presented indicate that this phenomenon appears to result from distension of deep medullary veins secondary to partial obstruction of venous outflow from elevated intracranial pressur...
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ژورنال
عنوان ژورنال: Journal of Biosciences and Medicines
سال: 2019
ISSN: 2327-5081,2327-509X
DOI: 10.4236/jbm.2019.73003